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"The Missoni family has been informed by the Venezuelan consulate that Vittorio Missoni and his wife are missing, but we don't know any more," the spokeswoman, Maddalena Aspes, said. "The authorities will resume their search for the plane in the morning."

Italian media reported that the plane went missing on Friday morning after takeoff from the resort of Los Roques, an island off the coast of Venezuela. Also reported to have been aboard the plane with Mr. Missoni, 58, and his wife, Maurizia Castiglioni, were another couple and two Venezuelan crew members.

Mr. Missoni is the son of the founders of the family-owned fashion house famous for its exuberantly colored knits, featuring bold stripes and zigzags. He owned the business with siblings Luca and Angela.